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Researchers at UVa. ID Genes that Influence Bone Density


May, 5, 2014

There's been a new breakthrough in the fight against osteoporosis.

Using mice, researchers at the University of Virginia have identified two genes that influence bone density.

By targeting those genes with therapeutics, doctors in the United States may be able to one day cure or prevent osteoporosis in humans.

"I think the next step for us from a scientific stand point will be to more clearly define the mechanism through which this novel regulator works and working on translating those results to humans and really understanding more of how it works and how we can target that to improve bone mass," said Dr. Charles Farber, Assistant Professor, Center for Public Health Genomics, University of Virginia.

Osteoporosis is a common bone disease.

In the United States, researchers say 12 million people have been diagnosed and another 30 million have low bone mass and are at risk of osteoporosis which results in 1.5 million fractures every year.


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