UVa. Developing New Drug

July 24, 2014

A new antibiotic being developed at the University of Virginia School of Medicine looks like it might be effective against a wide array of pathogens.

The new drug, Amixicile, combats Clostridium difficile, which is a dangerous super-bug that that lives in the gut and is drug resistant.

Amixicile works in a way that prevents the dangerous bacteria from become drug resistant, and it spares the good bacteria.

"It’s actually gets the bad guys and spares the good guys, and there is no drug resistance because the unique novel mechanism,” says Paul S. Hoffman, PH.D. with UVa. Division of Infectious Disease. “Conceivably you can give this drug heart medications, blood pressure medications for the life of the individual."

More pre-clinical work needs to be done before the researchers can gain FDA approval to begin testing Amixicile on people.


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