Mike Scott's senior night started with a thunderous ovation from Virginia fans, as the fifth-year senior was honored before Thursday's game against Florida State.
But Scott's night ended in bitter disappointment.
"We just gave that one away," Scott said, minutes after Ian Miller's three-pointer with a second to play gave the Seminoles a 63-60 win.
"That was our last chance to play the top teams in the ACC," Scott said. "We lost to Duke, UNC swept us, and Florida State already had a win against us so that was our last chance to beat one of the best teams. We had it but we gave it away."
Scott had a game-high 28 points and 10 rebounds in the loss.
The Cavaliers climbed out of a nine-point halftime hole to lead by as many as 11 in the second half. But Miller scored nine points during a game-ending 16-2 Seminole run over the game's final 4:10.
"I think we're all still a little shocked that we lost that one," said fellow senior Sammy Zeglinski. "We all thought we had it, but it just kind of slipped away at the end. We couldn't come up with any stops."
The Cavaliers' loss, combined with Clemson's 58-56 win at home over Virginia Tech on Thursday, creates a four-way tie for fourth place in the ACC standings. UVa, Clemson, Miami, and NC State are all 8-7 in the conference.
Virginia's final game of the regular season is 2 p.m. Sunday at Maryland.